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Sickle Cell Trait (SCT) FAQ

Sickle cell trait used to be thought of as a harmless genetic condition that didn't cause any problems in the people who had it. However, we are learning that people with sickle cell trait have a slightly higher risk of certain diseases in adulthood compared to others of the same age and ancestry. Learn more here.

Information about sickle cell disease is coming soon so check back often.

  • How does someone get SCT?
    Sickle cell trait (SCT) is inherited from parents, like hair and eye color.  We cannot tell which parent passed it down to your baby but each parent can get a simple blood test done to determine if they also have SCT or not.   If one parent has SCT (“AS”)...
  • What is sickle cell trait (SCT)?
    Sickle cell trait (SCT) occurs when of a person inherits one gene for normal hemoglobin (known as Hemoglobin A, or “Hb A”) from one parent and one abnormal hemoglobin, called Hemoglobin S (“Hb S”) from the other parent.  One normal Hb A gene is usually en...
  • How common is SCT?
    It depends but, in the United States, approximately 1 in 13 Black people or African Americans have sickle cell trait (SCT). In comparison, approximately 1 in 3 people in Sub-Saharan Africa have SCT. In the United States, people who identify as Hispanic, Ar...
  • Why is SCT so common?
    SCT protects against sever forms of malaria, an infection carried by mosquitoes. Therefore, SCT is most common in parts of the world where malaria is also common, namely Subsaharan and Equatorial Africa and Middle East. SCT is now worldwide as populations ...

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